Heyes, Derren J : rechercher sur Z-Library

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1

Stepwise Hydride Transfer in a Biological System: Insights into the Reaction Mechanism of the Light-Dependent Protochlorophyllide Oxidoreductase

Archipowa, Nataliya, Kutta, Roger, Heyes, Derren, Scrutton, Nigel

Journal:

Angewandte Chemie International Edition

Année:

2018

Langue:

english

Fichier:

PDF, 5.45 MB

english, 2018

2

Structural basis for enzymatic photocatalysis in chlorophyll biosynthesis

Zhang, Shaowei, Heyes, Derren J., Feng, Lingling, Sun, Wenli, Johannissen, Linus O., Liu, Huanting, Levy, Colin W., Li, Xuemei, Yang, Ji, Yu, Xiaolan, Lin, Min, Hardman, Samantha J. O., Hoeven, Robin,

Journal:

Année:

2019

Fichier:

PDF, 12.33 MB

2019

3

Solvent-Slaved Protein Motions Accompany Proton but Not Hydride Tunneling in Light-Activated Protochlorophyllide Oxidoreductase

Derren J. Heyes, Michiyo Sakuma, Nigel S. Scrutton

Journal:

Angewandte Chemie

Année:

2009

Langue:

english

Fichier:

PDF, 480 KB

english, 2009

4

Solvent-Slaved Protein Motions Accompany Proton but Not Hydride Tunneling in Light-Activated Protochlorophyllide Oxidoreductase

Derren J. Heyes, Michiyo Sakuma, Nigel S. Scrutton

Journal:

Angewandte Chemie International Edition

Année:

2009

Langue:

english

Fichier:

PDF, 480 KB

english, 2009

5

Molecular basis of halorespiration control by CprK, a CRP-FNR type transcriptional regulator

Colin Levy, Katharine Pike, Derren J. Heyes, M. Gordon Joyce, Krisztina Gabor, Hauke Smidt, John van der Oost, David Leys

Journal:

Molecular Microbiology

Année:

2008

Langue:

english

Fichier:

PDF, 1.45 MB

english, 2008

6

Ultrafast enzymatic reaction dynamics in protochlorophyllide oxidoreductase

Heyes, Derren J, Hunter, C Neil, van Stokkum, Ivo H M, van Grondelle, Rienk, Groot, Marie Louise

Journal:

Natural Structural Biology

Année:

2003

Langue:

english

Fichier:

PDF, 364 KB

english, 2003

7

Preparation and photophysical properties of a caged kynurenine

Chandan Maitrani, Derren J. Heyes, Sam Hay, Selvanathan Arumugam, Vladimir V. Popik, Robert S. Phillips

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2012

Langue:

english

Fichier:

PDF, 391 KB

english, 2012

8

Gating mechanisms for biological electron transfer: Integrating structure with biophysics reveals the nature of redox control in cytochrome P450 reductase and copper-dependent nitrite reductase

Nicole G.H. Leferink, Christopher R. Pudney, Sibylle Brenner, Derren J. Heyes, Robert R. Eady, S. Samar Hasnain, Sam Hay, Stephen E.J. Rigby, Nigel S. Scrutton

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 546 KB

english, 2012

9

Making light work of enzyme catalysis: protochlorophyllide oxidoreductase

Derren J. Heyes, C. Neil Hunter

Journal:

Trends in Biochemical Sciences

Année:

2005

Langue:

english

Fichier:

PDF, 498 KB

english, 2005

10

Kinetic and spectroscopic probes of motions and catalysis in the cytochrome P450 reductase family of enzymes

Christopher R. Pudney, Derren J. Heyes, Basile Khara, Sam Hay, Stephen E. J. Rigby, Nigel S. Scrutton

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 633 KB

english, 2012

11

O21. Ca2+-calmodulin exerts thermodynamic and conformational regulation over electron transport in nNOS

Andrew W. Munro, Adrian J. Dunford, Sam Hay, Derren J. Heyes, Anne-Marie Quinn, Stephen E.J. Rigby, Nigel S. Scrutton

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 57 KB

english, 2008

12

NADPH:protochlorophyllide oxidoreductase from Synechocystis: overexpression, purification and preliminary characterisation

Derren J. Heyes, Giles E.M. Martin, R.James Reid, C.Neil Hunter, Helen M. Wilks

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 134 KB

english, 2000

13

Conformational changes in an ultrafast light-driven enzyme determine catalytic activity

Sytina, Olga A., Heyes, Derren J., Hunter, C. Neil, Alexandre, Maxime T., van Stokkum, Ivo H. M., van Grondelle, Rienk, Groot, Marie Louise

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 269 KB

english, 2008

14

Simultaneous Measurements of Solvent Dynamics and Functional Kinetics in a Light-Activated Enzyme

Durin, Guillaume, Delaunay, Aude, Darnault, Claudine, Heyes, Derren J., Royant, Antoine, Vernede, Xavier, Hunter, C. Neil, Weik, Martin, Bourgeois, Dominique

Journal:

Biophysical Journal

Année:

2009

Langue:

english

Fichier:

PDF, 778 KB

english, 2009

15

Structural basis of kynurenine 3-monooxygenase inhibition

Amaral, Marta, Levy, Colin, Heyes, Derren J., Lafite, Pierre, Outeiro, Tiago F., Giorgini, Flaviano, Leys, David, Scrutton, Nigel S.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 937 KB

english, 2013

16

Identification and Characterization of the Product Release Steps within the Catalytic Cycle of Protochlorophyllide Oxidoreductase †

Heyes, Derren J., Hunter, C. Neil

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 156 KB

english, 2004

17

Kinetic characterisation of the light-driven protochlorophyllide oxidoreductase (POR) from Thermosynechococcus elongatus

McFarlane, Michael J., Hunter, C. Neil, Heyes, Derren J.

Journal:

Photochemical & Photobiological Sciences

Année:

2005

Langue:

english

Fichier:

PDF, 209 KB

english, 2005

18

Proton-Coupled Electron Transfer in the Catalytic Cycle of Alcaligenes xylosoxidans Copper-Dependent Nitrite Reductase

Leferink, Nicole G. H., Han, Cong, Antonyuk, Svetlana V., Heyes, Derren J., Rigby, Stephen E. J., Hough, Michael A., Eady, Robert R., Scrutton, Nigel S., Hasnain, S. Samar

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 4.51 MB

english, 2011

19

Protochlorophyllide Oxidoreductase: “Dark” Reactions of a Light-Driven Enzyme †

Heyes, Derren J., Ruban, Alexander V., Hunter, C. Neil

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 288 KB

english, 2003

20

Laser Photoexcitation of NAD(P)H Induces Reduction of P450 BM3 Heme Domain on the Microsecond Time Scale

Girvan, Hazel M., Heyes, Derren J., Scrutton, Nigel S., Munro, Andrew W.

Journal:

Journal of the American Chemical Society

Année:

2007

Langue:

english

Fichier:

PDF, 132 KB

english, 2007

21

Conformational Events during Ternary Enzyme−Substrate Complex Formation Are Rate Limiting in the Catalytic Cycle of the Light-Driven Enzyme Protochlorophyllide Oxidoreductase †

Heyes, Derren J., Menon, Binuraj R. K., Sakuma, Michiyo, Scrutton, Nigel S.

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 710 KB

english, 2008

22

Internal electron transfer in multi-site redox enzymes is accessed by laser excitation of thiouredopyrene-3,6,8-trisulfonate (TUPS)

Heyes, Derren J., Quinn, Anne-Marie, Cullis, Paul M., Lee, Michael, Munro, Andrew W., Scrutton, Nigel S.

Journal:

Chemical Communications

Année:

2009

Langue:

english

Fichier:

PDF, 638 KB

english, 2009

23

Protochlorophyllide Excited-State Dynamics in Organic Solvents Studied by Time-Resolved Visible and Mid-Infrared Spectroscopy

Sytina, Olga A., van Stokkum, Ivo H. M., Heyes, Derren J., Hunter, C. Neil, van Grondelle, Rienk, Groot, Marie Louise

Journal:

Journal of Physical Chemistry B

Année:

2010

Langue:

english

Fichier:

PDF, 1.65 MB

english, 2010

24

Excited state dynamics and catalytic mechanism of the light-driven enzyme protochlorophyllide oxidoreductase

Scrutton, Nigel S., Louise Groot, Marie, Heyes, Derren J.

Journal:

Physical Chemistry Chemical Physics

Année:

2012

Langue:

english

Fichier:

PDF, 1.73 MB

english, 2012

25

Modulation of ligand-heme reactivity by binding pocket residues demonstrated in cytochrome c' over the femtosecond-second temporal range

Russell, Henry J., Hardman, Samantha J. O., Heyes, Derren J., Hough, Michael A., Greetham, Gregory M., Towrie, Michael, Hay, Sam, Scrutton, Nigel S.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 967 KB

english, 2013

26

Carbon monoxide poisoning is prevented by the energy costs of conformational changes in gas-binding haemproteins

Svetlana V. Antonyuk, Neil Rustage, Christine A. Petersen, Jamie L. Arnst, Derren J. Heyes, Raman Sharma, Neil G. Berry, Nigel S. Scrutton, Robert R. Eady, Colin R. Andrew and S. Samar Hasnain

Journal:

Proceedings of the National Academy of Sciences

Année:

2011

Langue:

english

Fichier:

PDF, 1.23 MB

english, 2011

27

Excited-State Charge Separation in the Photochemical Mechanism of the Light-Driven Enzyme Protochlorophyllide Oxidoreductase

Heyes, Derren J., Hardman, Samantha J. O., Hedison, Tobias M., Hoeven, Robin, Greetham, Greg M., Towrie, Michael, Scrutton, Nigel S.

Journal:

Angewandte Chemie International Edition

Année:

2015

Langue:

english

Fichier:

PDF, 803 KB

english, 2015

28

The Photoinitiated Reaction Pathway of Full-length Cyanobacteriochrome Tlr0924 Monitored Over 12 Orders of Magnitude

Hauck, Anna F. E., Hardman, Samantha J. O., Kutta, Roger J., Greetham, Gregory M., Heyes, Derren J., Scrutton, Nigel S.

Journal:

Journal of Biological Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 4.54 MB

english, 2014

29

Comprehensive Analysis of the Green-to-Blue Photoconversion of Full-Length Cyanobacteriochrome Tlr0924

Hardman, Samantha J.O., Hauck, Anna F.E., Clark, Ian P., Heyes, Derren J., Scrutton, Nigel S.

Journal:

Biophysical Journal

Année:

2014

Langue:

english

Fichier:

PDF, 2.55 MB

english, 2014

30

Catalytic Mechanism of Cofactor-Free Dioxygenases and How They Circumvent Spin-Forbidden Oxygenation of Their Substrates

Hernández-Ortega, Aitor, Quesne, Matthew G., Bui, Soi, Heyes, Derren J., Steiner, Roberto A., Scrutton, Nigel S., de Visser, Sam P.

Journal:

Journal of the American Chemical Society

Année:

2015

Langue:

english

Fichier:

PDF, 2.37 MB

english, 2015

31

Light-driven biocatalytic reduction of α,β-unsaturated compounds by ene reductases employing transition metal complexes as photosensitizers

Peers, Martyn K., Toogood, Helen S., Heyes, Derren J., Mansell, David, Coe, Benjamin J., Scrutton, Nigel S.

Journal:

Catalysis Science & Technology

Année:

2015

Langue:

english

Fichier:

PDF, 390 KB

english, 2015

32

Excited-State Charge Separation in the Photochemical Mechanism of the Light-Driven Enzyme Protochlorophyllide Oxidoreductase

Heyes, Derren J., Hardman, Samantha J. O., Hedison, Tobias M., Hoeven, Robin, Greetham, Greg M., Towrie, Michael, Scrutton, Nigel S.

Journal:

Angewandte Chemie

Année:

2015

Langue:

english

Fichier:

PDF, 1.50 MB

english, 2015

33

Does the pressure dependence of kinetic isotope effects report usefully on dynamics in enzyme H-transfer reactions?

Hoeven, Robin, Heyes, Derren J., Hay, Sam, Scrutton, Nigel S.

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 875 KB

english, 2015

34

Cross-Species Analysis of Protein Dynamics Associated with Hydride and Proton Transfer in the Catalytic Cycle of the Light-Driven Enzyme Protochlorophyllide Oxidoreductase

Hoeven, Robin, Hardman, Samantha J. O., Heyes, Derren J., Scrutton, Nigel S.

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 4.38 MB

english, 2016

35

Isolation and characterisation of 13 pterosins and pterosides from bracken (Pteridium aquilinum (L.) Kuhn) rhizome

Mohammad, Rizgar Hassan, Nur-e-Alam, Mohammad, Lahmann, Martina, Parveen, Ifat, Tizzard, Graham J., Coles, Simon J., Fowler, Mark, Drake, Alex F., Heyes, Derren, Thoss, Vera

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2016

36

Multiple active site residues are important for photochemical efficiency in the light-activated enzyme protochlorophyllide oxidoreductase (POR)

Menon, Binuraj R.K., Hardman, Samantha J.O., Scrutton, Nigel S., Heyes, Derren J.

Journal:

Journal of Photochemistry and Photobiology B: Biology

Année:

2016

Langue:

english

Fichier:

PDF, 5.41 MB

english, 2016

37

Spectroscopic and kinetic characterization of the light-dependent enzyme protochlorophyllide oxidoreductase (POR) using monovinyl and divinyl substrates

Heyes, Derren J., Kruk, Jerzy, Hunter, C. Neil

Journal:

Biochemical Journal

Année:

2006

Langue:

english

Fichier:

PDF, 513 KB

english, 2006

38

Spectroscopic characterisation of the substrate binding properties of NADPH:protochlorophyllide oxidoreductase (POR)

Heyes, Derren J., Hunter, C. Neil

Journal:

Biochemical Society Transactions

Année:

2002

Langue:

english

Fichier:

PDF, 111 KB

english, 2002

39

Ultrafast catalytic processes and conformational changes in the light-driven enzyme protochlorophyllide oxidoreductase (POR)

Sytina, Olga A., Heyes, Derren J., Hunter, C. Neil, Groot, Marie Louise

Journal:

Biochemical Society Transactions

Année:

2009

Langue:

english

Fichier:

PDF, 245 KB

english, 2009

40

Conformational changes in the catalytic cycle of protochlorophyllide oxidoreductase: what lessons can be learnt from dihydrofolate reductase?

Heyes, Derren J., Scrutton, Nigel S.

Journal:

Biochemical Society Transactions

Année:

2009

Langue:

english

Fichier:

PDF, 97 KB

english, 2009

41

Engineering Proximal vs Distal Heme-NO Coordination via Dinitrosyl Dynamics: Implications for NO Sensor Design

Kekilli, Demet, Petersen, David, Pixton, David, Gahfoor, Dlzar, Abdullah, Gaylany Hikmat, Dworkowski, Florian, Wilson, Michael, Heyes, Derren, Hardman, Samantha, Murphy, Loretta, Strange, Richard Will

Journal:

Chemical Science

Année:

2016

Langue:

english

Fichier:

PDF, 1.61 MB

english, 2016

42

Excited-State Properties of Protochlorophyllide Analogues and Implications for Light-Driven Synthesis of Chlorophyll

Heyes, Derren J., Hardman, Samantha J. O., Mansell, David, Ní Cheallaigh, Aisling, Gardiner, John M., Johannissen, Linus O., Greetham, Gregory M., Towrie, Michael, Scrutton, Nigel S.

Journal:

Journal of Physical Chemistry B

Année:

2017

Langue:

english

Fichier:

PDF, 2.70 MB

english, 2017

43

Direct Evidence of an Excited-State Triplet Species upon Photoactivation of the Chlorophyll Precursor Protochlorophyllide

Brandariz-de-Pedro, Guillem, Heyes, Derren J., Hardman, Samantha J. O., Shanmugam, Muralidharan, Jones, Alex R., Weber, Stefan, Nohr, Daniel, Scrutton, Nigel S., Fielding, Alistair J.

Journal:

The Journal of Physical Chemistry Letters

Année:

2017

Langue:

english

Fichier:

PDF, 1.04 MB

english, 2017

44

Stepwise Hydride Transfer in a Biological System: Insights into the Reaction Mechanism of the Light-Dependent Protochlorophyllide Oxidoreductase

Archipowa, Nataliya, Kutta, Roger, Heyes, Derren, Scrutton, Nigel

Journal:

Angewandte Chemie

Année:

2018

Langue:

english

Fichier:

PDF, 5.45 MB

english, 2018

45

Photochemical mechanism of an atypical algal phytochrome

Scrutton, Nigel, Choudry, Uzma, Heyes, Derren, Hardman, Samantha, Sakuma, Michiyo, Sazanovich, Igor, Woodhouse, Joyce, De La Mora, Eugenio, Pederson, Martin, Wulff, Michael, Weik, Martin, Schiro, Gior

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 3.65 MB

english, 2018

46

Pressurized CO 2 as a carboxylating agent for the biocatalytic ortho -carboxylation of resorcinol

Plasch, Katharina, Hofer, Gerhard, Keller, Walter, Hay, Sam, Heyes, Derren J., Dennig, Alexander, Glueck, Silvia M., Faber, Kurt

Journal:

Green Chemistry

Année:

2018

Langue:

english

Fichier:

PDF, 677 KB

english, 2018

47

Photochemical Mechanism of an Atypical Algal Phytochrome

Choudry, Uzma, Heyes, Derren J., Hardman, Samantha J. O., Sakuma, Michiyo, Sazanovich, Igor V., Woodhouse, Joyce, De La Mora, Eugenio, Pedersen, Martin N., Wulff, Michael, Weik, Martin, Schirò, Giorgi

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 859 KB

english, 2018

48

Human Cryptochrome-1 Confers Light Independent Biological Activity in Transgenic Drosophila Correlated with Flavin Radical Stability

Vieira, Jacqueline, Jones, Alex R., Danon, Antoine, Sakuma, Michiyo, Hoang, Nathalie, Robles, David, Tait, Shirley, Heyes, Derren J., Picot, Marie, Yoshii, Taishi, Helfrich-Förster, Charlotte, Soubigo

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 569 KB

english, 2012

49

Mechanistic Reappraisal of Early Stage Photochemistry in the Light-Driven Enzyme Protochlorophyllide Oxidoreductase

Heyes, Derren J., Hardman, Samantha J. O., Mansell, David, Gardiner, John M., Scrutton, Nigel S., Subramanyam, Rajagopal

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2012

50

Ultrafast Red Light Activation of Synechocystis Phytochrome Cph1 Triggers Major Structural Change to Form the Pfr Signalling-Competent State

Heyes, Derren J., Khara, Basile, Sakuma, Michiyo, Hardman, Samantha J. O., O'Cualain, Ronan, Rigby, Stephen E. J., Scrutton, Nigel S., Wu, Min

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2012